The Inland Route known to the Indians and fur traders, also included Round Lake (near Lake Michigan), and a small stream from Round Lake to Crooked Lake called Iduna Creek. The Inland Route was a highly desirable passage, due to the naturally protected inland waters and eliminating the need to take the treacherous journey around Waugoshance Point on lake Michigan. Therefore, navigation of the Great Lakes waters between, Petoskey and the mouth of the Cheboygan River, could be eliminated by taking the Inland Route.

Indian encampments have been documented along the entire Inland Route. An archaeological study by Michigan State University has found traces of approximately 50 encampments along its shores. One of the most productive digs was located in Ponshewaing, with artifacts dating back 3000 years.

Two portage points were used by the trading Indians. The portage from Lake Michigan occurred near Menonaqua located between Kegomic and the south border of the current Petoskey State Park. Another portage was usually needed at various points on the Iduna Creek.